High levels of IB6 are often found in NSCLC, making it a good target for treatment. A preclinical study found that in lung cancer, IB6 was correlated with interleukin-8 levels and promoted cancer cell ...

2 Institute for Precision Health, University of Leicester, Leicester, UK 3 National Institute for Health Research Leicester Biomedical Research Centre, The Institute for Lung Health, University of ...

Collectively, the comprehensive body of work presented by Lemay et al provides a compelling argument for the important role of α5β1 integrin in mediating cell-specific responses in the right ...

Introduction: Spinal cord injury involves complex pathobiological mechanisms, necessitating a multidimensional approach for its cure. Previous studies have shown that α9-integrin expression and ...

The federal office in charge of ensuring cybersecurity at all levels of the government cited the use of encrypted messaging app Signal as a "best practice" for "highly targeted" government officials, ...

Medically reviewed by Mary Choy, PharmD Key Takeaways Biologic medications help reduce inflammation in ulcerative colitis. If you're new to biologics, infliximab might be your first option for ...

Immune system recognizes invading microbes at both pathogen and antigen levels. Toll-like receptors (TLRs) play a key role in the first-line defense against pathogens. Major functions of TLRs include ...

Defects in the blood vessel network of the central nervous system have been linked to early symptoms of neurodegenerative diseases such as Alzheimer's disease and amyotrophic lateral sclerosis (ALS).

From left to right, the experts Pilar Villacampa, Víctor Arribas and Eloi Montañez, from the Faculty of Medicine and Health Sciences of the University of Barcelona and IDIBELL. Defects in the blood ...

Adhesion of leukocytes to blood vessels, antigen-presenting cells, and target cells is critical to a wide range of immune functions. Adhesion is mediated by integrins on the cell surface, activity of ...