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If you experience severe lower back pain during your period, it may be because of PMS, PMDD, dysmenorrhea, or something more serious.

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Someone who has any kind of severe pain a year after a heart attack may be more likely to die within the eight years afterward, according to a new study. Someone in the US has a heart attack about ...

People taking medication for extreme pain may also have side effects that could be deadly, he said. Many painkillers, even ones sold over the counter, can increase the risk of cardiovascular problems.

Minor back pain during pregnancy usually requires no treatment. But if your back pain is severe, consult with your doctor soon, as it could be a pregnancy complication or other serious medical ...

Sickle cell pain crisis can have a sudden onset and cause extreme pain. Find out about home treatments, medications, and triggers here.

For now, most people needing relief from moderate to severe pain have two options: drugs like ibuprofen and COX-2 inhibitors, or opioids.