Brandon Aiyuk hasn't played an NFL game since his serious knee injury in 2024. Here's why he won't be playing at all in 2025.

The Tennessee Titans and the San Francisco 49ers meet Sunday in Week 15 in Santa Clara, California, with kickoff slated for 4 ...

Led by Amari McCottry's 18 points, the Saint Louis Billikens defeated the San Francisco Dons 85-75 on Saturday ...

Our experts' predictions are in for Tennessee Titans vs. San Francisco 49ers on Sunday. Here's who our experts are picking to ...

The Federal National Mortgage Association, or Fannie Mae, will move its San Francisco office to Birmingham, Alabama, ...

A large fire burned at a six-story residential building in San Francisco's Tenderloin District early Friday morning, leaving ...

June feels a long way away, but San Francisco’s Stern Grove Festival is already cooking up its summer lineup. On Friday, the ...

Fire officials say six people have been taken to hospitals after a gas explosion started a major fire in a San Francisco Bay ...

Nearly 80 lawsuits accusing videogame platform Roblox of knowingly facilitating child sexual exploitation will be centralized ...

For some businesses, Saturday is the most wonderful day of the year as thousands of Santas visit local watering holes for ...

Saleh reveals Clelin Ferrell's "relentless" impact on the 49ers defense. The pass rusher's explosive play and consistent ...

Food industry giants including General Mills, Nestle USA and Mars face historic lawsuit seeking restitution for public ...