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  1. Osteoarthritis - Diagnosis & treatment - Mayo Clinic

    Apr 8, 2025 · One of the most common reasons for knee replacement surgery is severe pain from joint damage caused by osteoarthritis. This condition can break down the slick cartilage that …

  2. Knee Arthritis - Mayo Clinic Orthopedics & Sports Medicine

    Knee osteoarthritis is a common condition that occurs when the protective cartilage in the knee wears down, while bone around the joint grows or loses its normal smooth contours.

  3. Osteoarthritis - Symptoms & causes - Mayo Clinic

    Apr 8, 2025 · Although osteoarthritis can damage any joint, the condition most commonly affects joints in the hands, knees, hips and spine. Osteoarthritis symptoms can usually be managed, …

  4. Progress in gene therapy offers hope for long-term knee pain relief

    Jul 28, 2025 · In the recent study, Dr. Evans and his team gave the experimental gene therapy to nine patients with osteoarthritis, delivering it directly into the knee joint. They found that the …

  5. Knee pain - Symptoms and causes - Mayo Clinic

    Jan 25, 2023 · But some knee injuries and medical conditions, such as osteoarthritis, can lead to increasing pain, joint damage and disability if left untreated. And having a knee injury — even …

  6. Mayo Clinic Q and A: When is it time for a knee replacement?

    Sep 6, 2024 · Knee osteoarthritis occurs when protective cartilage in the knee wears down leading to inflammation and pain. Commonly, patients will have bone spurs, and the normal …

  7. Analyzing the performance of platelet-rich plasma and bone …

    Feb 6, 2025 · In this Q and A, Stephen J. Wisniewski, M.D., discusses the status of research focused on the use of platelet-rich plasma (PRP) and bone marrow aspirate concentrate …

  8. Arthritis - Symptoms and causes - Mayo Clinic

    Aug 29, 2023 · The most common type of arthritis, osteoarthritis involves wear-and-tear damage to a joint's cartilage — the hard, slick coating on the ends of bones where they form a joint.

  9. Knee-pain treatment for osteoarthritis - Mayo Clinic Press

    Sep 11, 2025 · There are many potential reasons for knee pain, including other forms of arthritis. But if your knee pain is typically aggravated by activity and gets better with rest, it’s likely …

  10. Knee pain - Diagnosis and treatment - Mayo Clinic

    Jan 25, 2023 · Research suggests that acupuncture may help relieve knee pain caused by osteoarthritis. Acupuncture involves the placement of hair-thin needles into your skin at …