At the very end of the T-loop, the single-stranded telomere DNA is held onto a region of double-stranded DNA by the telomere strand disrupting the double-helical DNA, and base pairing to one of the two …

Aug 4, 2025 · The telomere’s role in aging becomes clear when you realize they’re not endlessly replenished. In most somatic (body) cells, telomeres shorten with every division, slowly ticking down …

4 days ago · A telomere is a region of repetitive DNA sequences at the end of a chromosome. Telomeres protect the ends of chromosomes from becoming frayed or tangled. Each time a cell …

While telomere shortening has been linked to the aging process, it is not yet known whether shorter telomeres are just a sign of aging like gray hair or actually contribute to aging.

Mar 30, 2025 · Telomere length varies between individual chromosomes, they do not have the same telomere length in all individuals. This can affect the measurement of telomeres.

5 days ago · This Review presents an updated view on telomeric chromatin as a dynamic structure with a specialized histone organization and discusses the mechanisms of its regulation by cis-acting …

Mar 8, 2019 · We’ll dive into the recent research surrounding telomere shortening, cancer, and aging. You’ll learn how diet, exercise, and stress management affect telomeres.

Several single nucleotide polymorphisms at different loci, identified through genome-wide association studies, influence inter-individual variation in telomere length. In addition to genetic factors, …

Nov 20, 2025 · telomere, segment of DNA occurring at the ends of chromosomes in eukaryotic cells (cells containing a clearly defined nucleus). Telomeres are made up of repeated segments of DNA …

Explore the biology of telomere shortening, a natural process that serves as a cellular clock, linking the integrity of our DNA to aging and long-term health.